TLC column and synthesis

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Linda Waldman's picture
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TLC column and synthesis

I don't like our current TLC/Column lab experiments.  I am interested to see if anyone has an experiment that has the students use TLC to determine the best solvent to use in a column to purify the products of a mixture from a reaction (preferably SN1, Sn2, E1, or E2).  They might then use the TLC to see how pure the purification made the mixture. Or following a reaction via TLC, where they have to pick a good solvent system.

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